The topic of this work is the conflict of interest and the responsibility of civil servants for violations of official duties. The first part of the paper deals with the conceptual, methodological and legal framework of conflict of interest with emphasis on corruption as one of the forms of conflict of interest. The paper seeks to clarify corruption as the most widespread form of conflict of interest as well as legal regulations and mechanisms to prevent conflicts of interest. The provisions of the Law on the Prevention of Conflict of Interest and the principles of the action determined by the Law are analyzed. Consideration is also given to manners of conduct of officials when in doubt as to the existence of conflicts of interest and examples of such unacceptable behavior in society. Furthermore, the competences of the Conflict of Interest Decision-making Committee, which is a permanent and independent state body for the performance of the work within the scope stipulated by the Law on Prevention of Conflict of Interest, are analyzed. In the second part of the paper, the responsibilities of civil servants for violations of official duties are analyzed. Violation of official duty constitutes a violation of special duties and authorizations of official relations as well as violation of integrity committed by the holders of official authority. The differences between light and severe violations of official duty and the foreseen criminal sanctions for violations of official duty have been clarified in detail. In addition, the paper deals with the entire course of the proceedings for violation of official duty, bodies authorized for implementation of the proceedings as well as the legal statute of limitation for initiating and conducting the proceedings for breach of official duty. In the third part, the paper deals with the definitions of the concept of ethics and the Code of Ethics of Civil Servants, which contains the ethical principles that civil servants should adhere to during the service. In addition, the paper analyzes the role of the central state administration body responsible for civil servants and the role of ethics commissioner in state bodies. In conclusion, the paper provides a statistical review of complaints about the unethical behavior of civil servants.