Motivation of employees is u crucial factor in human resources management, both in the private and public sectors. Employees as a human factor represent the most important resource within an organization, as their role and contribution have a significant impact on the success and sustainability of the organization. Employee motivation in the private and public sectors is based on different motivational actors that depend on individual preferences and values, as well as the specificities of each organization. In addition to motivational factors, motivational strategies are also important as they indicate how to motivate employees and thereby achieve desired goals. This is precisely why the success of every company depends to a large extent on whether employees are sufficiently motivated, as a motivated employee will deliver very good business results. A portion of this work will also be dedicated to the motivation of individuals with disabilities and employers who hire people with disabilities, which is crucial for achieving and inclusive work environment. Motivation in this context creates mutual benefits. Individuals with disabilities become more productive and satisfied members of the organization, while employers, in addition to financial incentives for employing people with disabilities, gain diversity of talent and perspectives that can enhance their business. It is extremely important for organizations to recognize these motivational factors in order to create a stimulating work environment for their employees can result in increased productivity and lower employee turnover, therefore the role of managers is crucial in ensuring a successful and motivating work organization.